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West Nile virus season: What you must know about spread, symptoms and prevention

Like it or not, mosquitoes have arrived for the summer — and beyond their annoying, itchy bites, they also bring the risk of disease, most notably the West Nile virus (WNV).

Since the West Nile virus first entered the U.S. in 1999, it has become the leading cause of mosquito-borne disease in the country, according to the Centers for Disease Control and Prevention (CDC).

Reports of the year’s first cases are starting to trickle in from across the U.S., with 13 infections and counting as of June 13, per the CDC’s most recent data posted on its website as of Sunday, June 18.

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Mosquito biting

Since the West Nile virus first entered the U.S. in 1999, it has become the leading cause of mosquito-borne disease in the country. (iStock)

One of the biggest misconceptions about the virus, according to Dr. Christian Sandrock, division vice chief of internal medicine at UCDavis Health Medical Center in Sacramento, California, is that humans are natural hosts or that they propagate disease.

“Humans and horses are inadvertently infected,” he told Fox News Digital via email. “This is largely a disease of birds and we can get infected, but we are not part of the host cycle.”

Although rare, there have been a very small number of cases when the virus was transmitted through an organ transplant, blood transfusion or from mother to baby during pregnancy, childbirth or breastfeeding.

Around one in five people will develop febrile illness, which is marked by a fever along with body aches, headache, joint pain, diarrhea, rash and/or vomiting. These symptoms usually go away on their own, but some people may have lingering weakness and fatigue months after infection.

West Nile virus

The West Nile virus is a flavivirus in the same family as yellow fever, dengue fever, Japanese encephalitis and the Zika virus. (iStock)

In rare cases — about one in every 150 infected people — the virus can lead to serious conditions affecting the nervous system, such as encephalitis (inflammation of the brain) or meningitis (inflammation of the membranes that surround the brain and spinal cord), the CDC states on its website.

Those who develop serious illness may experience headache, stiff neck, high fever, disorientation, vision loss, muscle weakness, convulsions, tremors, coma or paralysis, which occur when there is viral infection of the central nervous system. 

Those who have any change in personality or weakness of the legs and arms should seek medical attention immediately, said Sandrock. 

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“It is possible to get some prolonged symptoms that can look just like long COVID,” he warned.

Diagnosis and treatment

Those who think they might have been infected with WNV should be assessed by a health care provider, the CDC states.

Diagnosis of the infection can be made based on evaluation of symptoms, recent exposure to mosquitoes and testing of blood or spinal fluid.

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Prevalence of West Nile virus

Since the first U.S. case in 1999, the West Nile virus has had a presence in the country each year. The number of cases fluctuates each year — from as low as 21 in the year 2000 to a high of 9,862 in 2003, per the CDC.

After a spike to 5,674 infections in 2012, annual cases remained relatively steady at between 2,000 and 2,600 between 2013 and 2018.

Standing water

Generally speaking, the number of infections is limited by the number of mosquitoes, Dr. Marc Siegel told Fox News Digital. Health care providers will typically recommend treating symptoms with over-the-counter pain medications and getting plenty of rest and fluids. (iStock)

They dipped to 971 in 2019 and 731 in 2020, before rising again to 2,911 in 2021.

Another theory is that larger numbers of cases are seen in the wetter years, when there is a larger mosquito population, according to Thompson, who specializes in infectious diseases.

In some parts of California, counties are using drones to apply larvicide in unoccupied marshes to reduce the mosquito population, he said.

“This approach is much safer than going after adult mosquitoes in terms of effectiveness, environmental impact and the affect on wildlife,” Dr. Siegel said.

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