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Resistance training can alleviate Alzheimer’s disease symptoms, research suggests

Resistance training and physical exercise plays a role in alleviating symptoms of Alzheimer’s disease, researchers suggest. 

An article published in the journal Frontiers in Neuroscience said its beneficial effects serve as a “complementary treatment.”

The work’s Brazilian authors from the Federal University of São Paulo and the University of São Paulo conducted experiments with transgenic mice with a mutation responsible for buildup of beta-amyloid plaques in the brain, finding after four weeks of training that their brain tissue showed a decrease in formation of beta-amyloid plaques.

Alzheimer’s disease is partially characterized by amyloid plaques, which can lead to problems with brain function.

“This confirms that physical activity can reverse neuropathological alterations that cause clinical symptoms of the disease,” Henrique Correia Campos, first author of the article, told the São Paulo Research Foundation. The foundation helped to fund the research.

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A woman does weighted squats

Researchers believe resistance training exercises have anti-inflammatory benefits that could be a reason for their findings. (iStock)

They said they believe that anti-inflammatory effects of such training could be a primary reason for these results. 

Previous research from the University of Sydney has said such training can help protect brain areas especially vulnerable to Alzheimer’s disease up to one year later.

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