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{"id":4103,"date":"2024-04-13T10:07:37","date_gmt":"2024-04-13T10:07:37","guid":{"rendered":"https:\/\/aitesonics.com\/sir-ian-wilmut-who-cloned-dolly-the-sheep-has-died-164536893\/"},"modified":"2024-04-13T10:07:37","modified_gmt":"2024-04-13T10:07:37","slug":"sir-ian-wilmut-who-cloned-dolly-the-sheep-has-died-164536893","status":"publish","type":"post","link":"https:\/\/aitesonics.com\/sir-ian-wilmut-who-cloned-dolly-the-sheep-has-died-164536893\/","title":{"rendered":"Sir Ian Wilmut, who cloned Dolly the sheep, has died"},"content":{"rendered":"

Sir Ian Wilmut, the scientist who led the team that cloned Dolly the sheep<\/a> in 1996, has died at 79. The University of Edinburgh, where he served as a professor before his 2012 retirement, announced<\/a> his passing today. Dolly was the first successful cloning of a mammal from an adult somatic cell, demonstrating the viability of somatic cell nuclear transfer (SCNT). The controversial milestone helped pave the way for today\u2019s research on regenerative medicine.<\/p>\n

Born near Stratford-upon-Avon (also Shakespeare\u2019s birthplace) in 1944, Wilmut discovered an interest in biology while at school in Scarborough; he later switched his major at the University of Nottingham from agriculture to animal science, kicking off the work he would be most known for. His Ph.D. studies at the University of Cambridge foreshadowed his later breakthroughs, focusing on \u201cthe preservation of semen and embryos for freezing.\u201d In 1972, he became the first scientist to successfully freeze, thaw and transfer a calf embryo, which he called \u201cFrostie,\u201d to a surrogate mother.<\/p>\n

Wilmut\u2019s work at The Roslin Institute in Edinburgh continued to push the boundaries of animal genetics. He strived to create modified sheep that would produce milk with proteins that could treat human diseases. A year before Dolly, he successfully cloned two lambs (Megan and Morag) whose cells were taken from sheep embryos.<\/p>\n

Dolly\u2019s successful birth in 1996 marked the first time a mammal was successfully cloned from an adult cell. The scientifically groundbreaking announcement also set off a media firestorm as experts and casual observers wrestled with lab-made mammals\u2019 ethical implications. Specifically, many wondered: If they\u2019re doing sheep now, how long until they clone humans? Religious groups accused the researchers of \u201cplaying God.\u201d Even those who focused more on the natural world than supernatural ones worried about the potential for making \u201cdesigner humans\u201d or something out of The Island of Dr. Moreau<\/em>.<\/p>\n

While Dolly proved that cells could be used to create a copy of the animal they came from, Wilmut\u2019s next experiment proved that they could also be altered. Polly, born in 1997, was the first genetically modified cloned mammal. His team spliced the host\u2019s genes with a human gene to create a sheep that would produce a protein missing from people with hemophilia. Polly was Wilmut\u2019s last cloning experiment.<\/p>\n

Wilmut moved to the University of Edinburgh the following decade, focusing on using cloning to make stem cells for regenerative medicine. He was knighted in 2008 and retired in 2012. Wilmut was diagnosed with Parkinson\u2019s in 2018 and became a patron of a new research program at the university working to slow the disease\u2019s progression with next-gen therapies.<\/p>\n

According to<\/a> The Guardian<\/em>, Sir Ian is survived by his wife Sara, his children \u2014 Helen, Naomi and Dean \u2014 and his five grandchildren: Daniel, Matthew, Isaac, Tonja and Tobias.<\/p>\n","protected":false},"excerpt":{"rendered":"